Registration is open for the 12th annual Paws & Claws 5K to benefit the Baypath Humane Society in Hopkinton. The event — which will return live this year — will be held at 10:30 a.m. on Sunday, Oct. 17, at Hopkinton State Park. The event includes a division for those running/walking with a dog. For more information, visit baypathhumane.org.