Students who qualified for the regional science fair pose for a photo at the Hopkinton High School Science and Engineering Fair on Wednesday.

Hopkinton High School’s annual Science and Engineering Fair was held Wednesday.

First place went to Aarush Naik and Dylan Striek for “The GlycoCharge: A Translational Spectrophotometric Apparatus for Noninvasive Glucose Monitoring in Type II Diabetics.”

Taking second place was Emilia Graham for “Understanding the Immunomodulatory Effects of Echinacea Purpurea on the Innate Immune System of Caenorhabditis Elegans.”

Third place was awarded to Shrija Kumar for “Utilizing CBD as a Potential Therapeutic in Alzheimer’s Disease by Modeling in C.elegans: A Nematode for Studying Neurodegenerative Diseases.”

In addition to the three above, also qualifying for the regional science fair were:

— Garima Chauhan for “The AVINE: A Less Invasive Prototype for Diagnostic Venipuncture to Prevent Side Effects Associated with Intravenous Infiltration and Extravasation”;

— Miyu Hasegawa and Piyusha Majgaonkar for “The Effects of Terpene — a Plant Compound — on Reducing Lobaplatin-Induced Neurotoxicity”;

— Kaizar Rangwala for “Scientific Machine Learning and Photodynamic Therapy for Anticipation, Prevention and Mitigation of Harmful Algal Blooms”;

— Vaagmi Shukla for “Understanding Neurotoxicity: Drosophila Melanogaster as a Model for Memory Loss”;

— Alekhya Purma and Sreenidhi Rajesh for “Brown Dwarf Spectral Analysis via Ensemble Supervised Machine Learning and Absorption Line Matching”;

— Devanshi Agrawal and Sofia Dhayal for “Development and Application of a Respirometer to Measure Metabolic Reactions in Drosophila Melanogaster”;

— Kaïs Guessab and David Priefer for “From Worms to Humans: Developing Acid-Resistant Casing for Novel Alzheimer’s Drug Delivery”;

— Simrit Kukreja and Aryan Shah for “Post-Transcriptional Regulation of Huntington’s Disease: An Antisense Oligonucleotide Therapeutic Strategy for Inhibiting Mutant Exon 1 Expression”;

— Arshia Aggarwal for “Investigating the Impact of Growth Agar on Ideonella Sakaiensis Efficiency.”

The Valerie Lechtanski Prize for Perseverance went to Madhav Warrier and Aarush Naik for “Modeling Combustion-Induced Oxidative Stress in Drosophila Melanogaster.”